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Additional benefits can improve the chances of success in fertility treatment
Please note our personal recommendations!
Progress in reproductive medicine enables us to keep improving our high standards. In accordance with the current state of science, we therefore recommend selected additional services in individual casesthat can further improve your individual chances. Please note: additional services are generally not paid for by statutory health insurances (GKV), even if they can be shown to increase the success of the treatment and meet the economic efficiency requirement (SGB V §12). Here we only present additional services that we are convinced of.
We only carry out all additional services on request, as the statutory health insurance companies do not contribute to the costs. This even applies to cryopreservation. Private health insurers cover the costs individually.
Cryopreservation - a new opportunity without further hormone treatment
If there are more viable cells after an egg puncture than are necessary for the planned embryo transfer, these excess cells can be frozen. This makes it possible (for example after the birth of a child) to carry out another embryo transfer without any hormone treatment, surgical egg retrieval and without further fertilization in the test tube.
At our center, egg cells are cryopreserved exclusively using the new process of vitrification. The survival rate of the cells is around 98%. The pregnancy rates in qualified fertility centers correspond to the rates in the fresh cycle, and are sometimes even higher.
With the help of cryopreservation, the pregnancy rate per egg retrieval is significantly increased. At the same time, women's health is protected by avoiding stressful hormone treatments. Furthermore, children after an embryo transfer of thawed cells are less often underweight at birth than children after a transfer of freshly obtained cells. This may be due to more natural implantation conditions without prior hormone stimulation.
Sperm maturity test - HBA test and PICSI
In intracytoplasmic sperm injection (ICSI), a mobile sperm cell is inserted (injected) into a mature egg cell with a fine glass pipette. For this injection, our laboratory assistants select mobile sperm cells with a normal appearance. The best fertilization results with ongoing pregnancies can always be achieved when really mature sperm cells are injected into the egg cell. Finding these mature sperm cells is now reliably possible with a new process: Because nature has set it up in such a way that only mature sperm cells can attach to the egg cell. They dock on the hyaluronan that naturally surrounds the egg cell. In physiological ICSI, also called PICSI for short, only the sperm cells that have bound to the hyaluronan drops in the PICSI bowl are inserted into the egg cells.
With the so-called sperm-hyaluronan bond test (HBA test) can already be found out during the preliminary diagnosis whether the Proportion of mature sperm cells is reduced and then a PICSI is demonstrably beneficial.
Embryo culture at the highest level of safety - EmbryoScope
Culture conditions close to the body are important for the good development of embryos. The oxygen content in the incubator plays an often neglected role here. Because oxygen is a cell poison. - We therefore produce one in the incubators at our center oxygen-reduced environmentthat approximates the conditions in the uterus. This is just one example of how we are doing everything we can to optimize the conditions for a high birth rate in our center.
Ideally, the embryos should remain in the incubator until they are transferred. However, because of the necessary fertilization controls, they must be removed and checked from time to time. However, these disruptions can now be avoided. Because incubators like our EmbryoScope allow a control without the culture dish having to be removed from the incubator. One in that EmbryoScope Integrated microscope with connected camera enables time-lapse recordings of the egg cells and embryos with the incubator closed. In this way, we can assess the cells on the monitor without any external interference and identify any developmental disorders in advance.
If more cells develop than intended for the embryo transfer, an extended embryo culture for 4-5 days is usually advisable (Blastocyst culture). If the embryos continue to grow during this time without any abnormalities, it has been proven that they can develop further until the embryo transfer.
Each embryo is surrounded by a protective covering (zona) until shortly before implantation in the uterus. When this shell is hardened, an embryo cannot easily slip out of the shell and implant itself. This can be seen under the microscope, and then opening the egg shell (assisted hatching) with a laser is helpful. This hatching aid is generally useful for defrosting.
EmbryoGlue is an embryo transfer solution that uses biomechanical signals to make it easier for the embryo to adhere to the uterine lining. EmbryoGlue improves the implantation of the embryo in the uterus and thus increases the pregnancy rate.
In women who have had repeated miscarriages, this special nutrient solution supports successful implantation by influencing the immune system in the uterine lining. It contains the messenger substance GM-CSF
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